- 20665-1-AP - Proteintech Group DLG4 antibody (2024)

Submitted referencesThe circRNA circ-Nbea participates in regulating diabetic encephalopathy.

Liu J, Deng Z, Yu Z, Zhou W, Yuan Q
Brain research 2022 Jan 1;1774:147702

Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.

Zhang D, Shen Q, Wu X, Xing D
Oxidative medicine and cellular longevity 2021;2021:6678276

Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model.

Abdoulaye IA, Wu SS, Chibaatar E, Yu DF, Le K, Cao XJ, Guo YJ
Neural plasticity 2021;2021:6635084

Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells.

Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, Saribas S, Zhu Y, Li F, Wang X, Yang W, Li Q, Ho WZ, Hu W
Frontiers in cellular neuroscience 2021;15:682272

Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in Mice.

Zhou L, Tao X, Pang G, Mu M, Sun Q, Liu F, Hu Y, Tao H, Li B, Xu K
Frontiers in pharmacology 2021;12:661304

Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.

Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66

Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.

Lan J, Hu Y, Wang X, Zheng W, Liao A, Wang S, Li Y, Wang Y, Yang F, Chen D
Neuropharmacology 2021 Sep 15;196:108689

Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus.

Lu C, Liu X, Li J, Huang Y, Huang X, Dai G, Wu L
ACS chemical neuroscience 2021 Oct 20;12(20):3939-3946

Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathway.

Lu L, Wang H, Liu X, Tan L, Qiao X, Ni J, Sun Y, Liang J, Hou Y, Dou H
Journal of neuroinflammation 2021 Oct 13;18(1):229

The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice.

Guo H, Deji C, Peng H, Zhang J, Chen Y, Zhang Y, Wang Y
Genes, brain, and behavior 2021 Nov;20(8):e12765

Novel Botanical Therapeutic NB-02 Effectively Treats Alzheimer's Neuropathophysiology in an APP/PS1 Mouse Model.

Lee YF, Lariviere L, Russ AN, Choi SZ, Bacskai BJ, Kastanenka KV
eNeuro 2021 May-Jun;8(3)

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.

Wang C, Xiong M, Gratuze M, Bao X, Shi Y, Andhey PS, Manis M, Schroeder C, Yin Z, Madore C, Butovsky O, Artyomov M, Ulrich JD, Holtzman DM
Neuron 2021 May 19;109(10):1657-1674.e7

Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.

Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8

Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.

Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414

Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca²⁺-Activin A circuit in chronic cerebral hypoperfusion rats.

Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761

MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies.

Li Y, Fan C, Wang L, Lan T, Gao R, Wang W, Yu SY
The Journal of clinical investigation 2021 Aug 16;131(16)

hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.

Akinyemi AR, Li D, Zhang J, Liu Q
Neuroscience letters 2021 Apr 23;751:135824

Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats.

Liao D, Lv C, Cao L, Yao D, Wu Y, Long M, Liu N, Jiang P
Oxidative medicine and cellular longevity 2020;2020:9268083

Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats.

Zhu S, Min D, Zeng J, Ju Y, Liu Y, Chen X
Stem cells international 2020;2020:6393075

Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.

Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Mediators of inflammation 2020;2020:5458061

Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling.

Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, Qiu J, Ke H, Yin S, Chen W, Wang Z
Frontiers in pharmacology 2020;11:204

Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1.

Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Neurochemistry international 2020 Oct;139:104789

Spinosin protects N2a cells from H₂ O₂ -induced neurotoxicity through inactivation of p38MAPK.

Xu F, Zhang X, Wang J, Li X, He B, Xiao F, Yan T, Wu B, Jia Y, Wang Z
The Journal of pharmacy and pharmacology 2020 Nov;72(11):1607-1614

The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.

Niu L, Luo SS, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong XL, Liu ZH, Zeng JY, Cao WY, Wan W
Neurobiology of learning and memory 2020 Nov;175:107301

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice.

Kukharsky MS, Ninkina NN, An H, Telezhkin V, Wei W, Meritens CR, Cooper-Knock J, Nakagawa S, Hirose T, Buchman VL, Shelkovnikova TA
Translational psychiatry 2020 May 28;10(1):171

The novel GLP-1/GIP analogue DA5-CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD.

Li C, Liu W, Li X, Zhang Z, Qi H, Liu S, Yan N, Xing Y, Hölscher C, Wang Z
Brain and behavior 2020 Mar;10(3):e01505

Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.

Zhang X, Zhao D, Wu W, Ali Shah SZ, Lai M, Yang D, Li J, Guan Z, Li W, Gao H, Zhao H, Zhou X, Yang L
Aging 2020 Jun 10;12(11):11139-11151

Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA₂ phosphorylation in experimental ischemic stroke.

Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467

Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.

Ye Q, Zeng C, Luo C, Wu Y
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670

Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity via the phosphoinositide 3-kinase/Akt pathway.

Yang F, Zhang Y, Tang Z, Shan Y, Wu X, Liu H
Life sciences 2020 Feb 1;242:117151

Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves.

Shi B, Luo J, Fang Y, Liu X, Rao Z, Liu R, Zeng N
Frontiers in pharmacology 2019;10:1324

Naloxone reversed cognitive impairments induced by repeated morphine under heavy perceptual load in the 5-choice serial reaction time task.

Guo H, Xie Q, Cui J, Xu D, Deji C, Chen Y, Wang Y, Lai J
Journal of neuroscience research 2019 Sep;97(9):1051-1065

Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease.

Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, Wang Y, Hua X, Han J, Zhou Y, Jin G, Yang X, Shi H, Zhang Z, Hua F
Aging 2019 Sep 11;11(17):7257-7273

Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.

Li PJ, Guo YQ, Ding PY, Liu RB, Deng F, Feng XX, Yan WJ
Neurological research 2019 Oct;41(10):867-874

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.

Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)

SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.

Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6

CAMK2-Dependent Signaling in Neurons Is Essential for Survival.

Kool MJ, Proietti Onori M, Borgesius NZ, van de Bree JE, Elgersma-Hooisma M, Nio E, Bezstarosti K, Buitendijk GHS, Aghadavoud Jolfaei M, Demmers JAA, Elgersma Y, van Woerden GM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 10;39(28):5424-5439

S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA₂ phosphorylation.

Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161

Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway.

Jiang P, Li G, Zhou X, Wang C, Qiao Y, Liao D, Shi D
Chemosphere 2019 Jan;214:430-435

Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.

Wang Y, Liu Y, Li Y, Liu B, Wu P, Xu S, Shi H
Acta histochemica 2019 Jan;121(1):56-63

PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.

Mo J, Wang B, Zhu X, Wu X, Liu Y
Neurobiology of disease 2019 Jan;121:274-285

The overexpression of GRASP might inhibit cell proliferation and invasion in hepatocellular carcinoma.

Cheng Y, Yin B, Hou T, Chen T, Ping J
Journal of cellular physiology 2019 Feb 19;

Protective mechanism of testosterone on cognitive impairment in a rat model of Alzheimer's disease.

Yan XS, Yang ZJ, Jia JX, Song W, Fang X, Cai ZP, Huo DS, Wang H
Neural regeneration research 2019 Apr;14(4):649-657

The protective mechanism underlying phenylethanoid glycosides (PHG) actions on synaptic plasticity in rat Alzheimer's disease model induced by beta amyloid 1-42.

Jia JX, Yan XS, Song W, Fang X, Cai ZP, Huo DS, Wang H, Yang ZJ
Journal of toxicology and environmental health. Part A 2018;81(21):1098-1107

Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.

Wu Z, Li X, Zhang Y, Tong D, Wang L, Zhao P
Frontiers in cellular neuroscience 2018;12:122

The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.

Raihan O, Brishti A, Molla MR, Li W, Zhang Q, Xu P, Khan MI, Zhang J, Liu Q
Neuroscience 2018 Oct 15;390:160-173

Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.

Zhu B, Zhao L, Luo D, Xu D, Tan T, Dong Z, Tang Y, Min Z, Deng X, Sun F, Yan Z, Chen G
Cellular and molecular life sciences : CMLS 2018 Jul;75(13):2473-2488

ZDHHC8 critically regulates seizure susceptibility in epilepsy.

Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, Wang W, He M, Zhou R, Ma Y, Xu D, Tian X, Gao X, Wang Q, Wang X
Cell death & disease 2018 Jul 23;9(8):795

Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.

Reddy PH, Yin X, Manczak M, Kumar S, Pradeepkiran JA, Vijayan M, Reddy AP
Human molecular genetics 2018 Jul 15;27(14):2502-2516

DLP1-dependent mitochondrial fragmentation and redistribution mediate prion-associated mitochondrial dysfunction and neuronal death.

Li C, Wang D, Wu W, Yang W, Ali Shah SZ, Zhao Y, Duan Y, Wang L, Zhou X, Zhao D, Yang L
Aging cell 2018 Feb;17(1)

Regulation of hippocampal long term depression by Neuroligin 1.

Dang R, Qi J, Liu A, Ren Q, Lv D, Han L, Zhou Z, Cao F, Xie W, Jia Z
Neuropharmacology 2018 Dec;143:205-216

Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model.

Chavez-Valdez R, Emerson P, Goffigan-Holmes J, Kirkwood A, Martin LJ, Northington FJ
Hippocampus 2018 Aug;28(8):617-630

Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ_1-42-Induced Rat Model of Alzheimer's Disease.

Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z
BioMed research international 2017;2017:7464872

Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.

Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128

Protective effects of Bushen Tiansui decoction on hippocampal synapses in a rat model of Alzheimer's disease.

Hui S, Yang Y, Peng WJ, Sheng CX, Gong W, Chen S, Xu PP, Wang Z
Neural regeneration research 2017 Oct;12(10):1680-1686

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.

Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c.

Chen YC, Kuo HY, Bornschein U, Takahashi H, Chen SY, Lu KM, Yang HY, Chen GM, Lin JR, Lee YH, Chou YC, Cheng SJ, Chien CT, Enard W, Hevers W, Pääbo S, Graybiel AM, Liu FC
Nature neuroscience 2016 Nov;19(11):1513-1522

NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.

Zhang Y, Chen G, Gao B, Li Y, Liang S, Wang X, Wang X, Zhu B
Scientific reports 2016 Nov 23;6:37713

REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.

Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, Yang L, Zhao D
Oncotarget 2016 Mar 15;7(11):12035-52